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ANTIINFECTIVES FOR SYSTEMIC USE › VACCINES › VIRAL VACCINES › Other viral vaccines
enterovirus 71 vaccines
J07BX06
Forms & Strengths
- inactivated whole virus vaccine
- live attenuated vaccine
- recombinant vaccine
- 0.5ml solution for injection
Adult Dosing
- not indicated for Routine Use in Adults
- dosing determined by specific vaccine product
- booster doses may be recommended
Pediatric Dosing
- primary series: 2 doses, 1-2 months apart, from 6-71 months of age
- booster dose: 1 dose, 1 year after primary series
- specific dosing by vaccine product and age group
Indications
- prevention of enterovirus 71 (EV-71) infections
- protection against EV-71-associated hand, foot, and mouth disease
- reduction of risk of EV-71-related neurological complications
Mechanism of Action
- induction of neutralizing antibodies against EV-71
- cell-mediated immune response
- prevention of EV-71 viral replication
Contraindications
- history of allergic reaction to vaccine components
- severe allergic reaction to previous dose of vaccine
- immunocompromised individuals: caution and consultation recommended
Adverse Reactions
- pain, redness, swelling at injection site
- low-grade fever
- fatigue
- nausea and vomiting
Drug Interactions
- concurrent administration with other vaccines: no interference expected
- immunosuppressive therapy: potential for reduced immune response
- blood products and immunoglobulins: potential interference with immune response
Curated Content: Needs Vetting Before Put to Clinical Use