← Search & browse all drugs
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS › ENDOCRINE THERAPY › HORMONES AND RELATED AGENTS › Estrogens
ethinylestradiol
L02AA03
Forms & Strengths
- Tablets: 10-50 mcg
- Transdermal patches: 20-100 mcg/day
- Vaginal rings: 6.5-15 mcg/day
- Injectable solutions: 1-5 mg/mL
Adult Dosing
- Contraception: 20-35 mcg/day
- Menstrual regulation: 20-50 mcg/day
- Hormone replacement therapy: 10-25 mcg/day
Pediatric Dosing
- Not recommended for children under 16 years
- For girls 16 years and older: same as adult dosing
Indications
- Contraception
- Menstrual regulation
- Hormone replacement therapy
- Dysmenorrhea
- Endometriosis
Mechanism of Action
- Estrogen receptor agonist
- Regulates menstrual cycle and fertility
- Inhibits gonadotropin secretion
- Stimulates endometrial growth
Contraindications
- Pregnancy and lactation
- Thromboembolic disorders
- Liver disease
- Breast cancer
- Undiagnosed vaginal bleeding
Adverse Reactions
- Nausea
- Vomiting
- Breast tenderness
- Headache
- Mood changes
- Thromboembolism
Drug Interactions
- Inducers of CYP3A4 (e.g., rifampicin, phenytoin)
- Inhibitors of CYP3A4 (e.g., ketoconazole, erythromycin)
- Anti-coagulants (e.g., warfarin)
- Hypertensives (e.g., ACE inhibitors)
- Antibiotics (e.g., penicillins, tetracyclines)
Curated Content: Needs Vetting Before Put to Clinical Use