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MUSCULO-SKELETAL SYSTEM › TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN › TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN › Antiinflammatory preparations, non-steroids for topical use
dexketoprofen
M02AA27
Forms & Strengths
- Tablets: 25mg
- Oral solution: 25mg/5mL
- Injectable solution: 50mg/2mL
Adult Dosing
- 25mg every 4-6 hours as needed
- Maximum daily dose: 150mg
- Oral solution: 25mg/5mL, 5mL every 4-6 hours as needed
Pediatric Dosing
- Not recommended for children under 18 years of age
Indications
- Treatment of mild to moderate pain
- Short-term treatment of moderate pain
- Relief of symptoms associated with primary dysmenorrhea
Mechanism of Action
- Inhibition of prostaglandin synthesis by selectively blocking COX-1 and COX-2 enzymes
- Reduces inflammation, pain, and fever
Contraindications
- Known hypersensitivity to dexketoprofen or other NSAIDs
- Active peptic ulcer disease
- Last trimester of pregnancy
Adverse Reactions
- Gastrointestinal upset
- Nausea and vomiting
- Dizziness and headache
- Hypertension and edema
Drug Interactions
- Increased risk of bleeding with anticoagulants and antiplatelet agents
- Concomitant use with other NSAIDs may increase the risk of gastrointestinal toxicity
- May interact with beta blockers, ACE inhibitors, and diuretics to increase the risk of hypertension and renal impairment
Curated Content: Needs Vetting Before Put to Clinical Use