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MUSCULO-SKELETAL SYSTEM › MUSCLE RELAXANTS › MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS › Other centrally acting agents
pridinol
M03BX03
Forms & Strengths
- Tablet: 4 mg
- Solution for injection: 2 mg/mL
Adult Dosing
- Oral: 4 mg 1 to 3 times daily
- Intramuscular/Intravenous: 2 to 4 mg up to 3 times daily in acute muscle spasms
Pediatric Dosing
- Safety and efficacy in pediatric patients have not been established; use is generally not recommended
Indications
- Symptomatic treatment of painful muscle spasms
- Adjunct in the treatment of acute torticollis, lumbago, and sciatica
Mechanism of Action
- Centrally acting skeletal muscle relaxant
- Exerts anticholinergic and sympathomimetic properties to reduce muscle tone and reflex spasm
Contraindications
- Hypersensitivity to pridinol or any component
- Angle-closure glaucoma
- Prostatic hypertrophy with urinary retention
- Mechanical stenosis in the gastrointestinal tract
- Megacolon
- First trimester of pregnancy and lactation
Adverse Reactions
- Dry mouth
- Blurred vision
- Tachycardia
- Urinary retention
- Constipation
- Drowsiness
- Dizziness
- Mild hypotension
Drug Interactions
- Anticholinergic agents (may potentiate antimuscarinic side effects)
- Central nervous system depressants and alcohol (may enhance sedation)
- Phenothiazines and tricyclic antidepressants (additive anticholinergic effects)
Curated Content: Needs Vetting Before Put to Clinical Use