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NERVOUS SYSTEM › ANALGESICS › ANTIMIGRAINE PREPARATIONS › Calcitonin gene-related peptide (CGRP) antagonists
eptinezumab
N02CD05
Forms & Strengths
- 100mg/mL solution for injection in a 10mL vial
Adult Dosing
- 100mg IV every 3 months
- Dosing should be individualized and titrated to the patient's needs
Pediatric Dosing
- Not established for patients under 18 years of age
Indications
- Prevention of episodic migraine
- Chronic migraine prevention
Mechanism of Action
- Monoclonal antibody that binds to calcitonin gene-related peptide
- Blocks the biological activity of calcitonin gene-related peptide
Adverse Reactions
- Hypersensitivity reactions
- Nausea
- Constipation
- Injection site reactions
Drug Interactions
- No significant interactions identified to date
- Potential increased risk of hypersensitivity reaction with concomitant other monoclonal antibodies
Curated Content: Needs Vetting Before Put to Clinical Use