← Search & browse all drugs

oxetorone

N02CX06

Forms & Strengths

tablet: 5mg, 10mg
solution for injection: 5mg/mL, 10mg/mL
suppository: 5mg, 10mg

Adult Dosing

30-60mg/day in divided doses for moderate pain
60-120mg/day in divided doses for severe pain
maximum dose: 120mg/day

Pediatric Dosing

0.5-1mg/kg every 4-6 hours for moderate pain
1-2mg/kg every 4-6 hours for severe pain
not recommended for children under 6 months

Indications

management of moderate to severe pain
treatment of chronic pain
pain relief in cancer patients

Mechanism of Action

selective agonist of mu-opioid receptors
inhibits release of substance P
activates G-protein coupled receptors

Contraindications

hypersensitivity to oxycodone or other opioids
respiratory depression
acute bronchial asthma
paralytic ileus

Adverse Reactions

nausea and vomiting
constipation
drowsiness
respiratory depression
dependency and addiction

Drug Interactions

increased sedation with CNS depressants
increased risk of constipation with anticholinergics
decreased efficacy with opioid antagonists
increased risk of respiratory depression with benzodiazepines

Curated Content: Needs Vetting Before Put to Clinical Use