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NERVOUS SYSTEM › ANTI-PARKINSON DRUGS › ANTICHOLINERGIC AGENTS › Ethers of tropine or tropine derivatives
benzatropine
N04AC01
Forms & Strengths
- Tablets: 0.5mg, 1mg, 2mg
- Injection: 1mg/mL
Adult Dosing
- Parkinsonism: 1-2mg orally 2-3 times daily
- Extrapyramidal reactions: 1-2mg IV/IM, repeat in 1 hour if needed
Pediatric Dosing
- Children over 3 years: 0.02-0.05mg/kg/dose orally 2-3 times daily
Indications
- Treatment of parkinsonism
- Treatment of extrapyramidal reactions
- Prevention of extrapyramidal reactions
Mechanism of Action
- Blocks acetylcholine receptors in the central nervous system
- Inhibits parasympathetic activity
Contraindications
- Hypersensitivity to benzatropine
- Narrow-angle glaucoma
- Myasthenia gravis
Adverse Reactions
- Dry mouth
- Dizziness
- Blurred vision
- Urinary retention
- Constipation
Drug Interactions
- Potentiates antihistamines and other anticholinergic agents
- May decrease effectiveness of phenothiazines
Curated Content: Needs Vetting Before Put to Clinical Use