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NERVOUS SYSTEM › PSYCHOLEPTICS › ANXIOLYTICS › Carbamates
emylcamate
N05BC03
Forms & Strengths
- Tablets: 200mg, 400mg
- Liquid: 200mg/5mL
Adult Dosing
- Initial dose: 200mg PO tid
- Maintenance dose: 400mg PO tid-qid
- Maximum daily dose: 1200mg
Pediatric Dosing
- Not recommended for children under 6 years old
- 6-12 years: Initial dose: 100mg PO tid, Maximum daily dose: 600mg
Indications
- Short-term treatment of anxiety
- Muscle relaxation
- Sedation
Mechanism of Action
- Acts as a GABA receptor agonist
- Enhances chloride ion influx into the neurons
- Produces sedative, hypnotic, and muscle relaxant effects
Contraindications
- Hypersensitivity to emylcamate
- Acute angle-closure glaucoma
- Severe respiratory depression
Adverse Reactions
- Drowsiness
- Dizziness
- Ataxia
- Blurred vision
- Gastrointestinal upset
Drug Interactions
- CNS depressants (e.g., alcohol, benzodiazepines): additive sedative effects
- Opioids: increased risk of respiratory depression
- Antihistamines: increased risk of sedation
Curated Content: Needs Vetting Before Put to Clinical Use