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NERVOUS SYSTEM › PSYCHOLEPTICS › HYPNOTICS AND SEDATIVES › Aldehydes and derivatives
dichloralphenazone
N05CC04
Forms & Strengths
- Dichloralphenazone 100mg capsules
- Dichloralphenazone 200mg tablets
Adult Dosing
- 50-100mg every 4-6 hours as needed
- Maximum dose: 400mg in 24 hours
Pediatric Dosing
- Not established for children under 12 years
- For children over 12 years: same as adult dosing
Indications
- Short-term treatment of insomnia
- Relief of anxiety and tension
Mechanism of Action
- Acts on the central nervous system to produce sedative and hypnotic effects
- Inhibits the activity of neurons that cause anxiety and insomnia
Contraindications
- Hypersensitivity to dichloralphenazone
- Acute intermittent porphyria
- Severe respiratory depression
Adverse Reactions
- Drowsiness
- Dizziness
- Headache
- Nausea
- Dry mouth
Drug Interactions
- Enhanced sedation with other CNS depressants
- Increased risk of respiratory depression with opioids
- Interactions with MAOIs and other sedatives
Curated Content: Needs Vetting Before Put to Clinical Use