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RESPIRATORY SYSTEM › NASAL PREPARATIONS › DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE › Antiallergic agents, excl. corticosteroids
nedocromil
R01AC07
Adult Dosing
- Allergic rhinitis: 1 spray in each nostril 2 to 4 times daily
Pediatric Dosing
- Children >= 6 years: 1 spray in each nostril 2 to 4 times daily
- Children < 6 years: Safety and efficacy not established
Indications
- Prophylaxis and treatment of seasonal allergic rhinitis
Mechanism of Action
- Mast cell stabilizer that inhibits the release of mediators (such as histamine and leukotrienes) from mast cells involved in allergic reactions
Contraindications
- Hypersensitivity to nedocromil or any component of the formulation
Adverse Reactions
- Transient burning or stinging upon application
- Nasal irritation
- Headache
- Unpleasant taste
- Nausea
Drug Interactions
- No clinically significant pharmacokinetic drug interactions reported due to minimal systemic absorption
Curated Content: Needs Vetting Before Put to Clinical Use