← Search & browse all drugs
RESPIRATORY SYSTEM › THROAT PREPARATIONS › THROAT PREPARATIONS › Antiseptics
ambazone
R02AA01
Adult Dosing
- Allow 1 lozenge to dissolve slowly in the mouth 3 to 5 times daily
- Do not swallow or chew immediately; allow maximal local contact time
- Maximum duration of treatment without medical re-evaluation: 3 to 5 days
Pediatric Dosing
- Children over 6 years: 1 lozenge 3 times daily, allowed to dissolve slowly in the mouth
- Not recommended for children under 6 years due to risk of choking
Indications
- Local symptomatic treatment of acute inflammatory conditions of the mouth and pharynx
- Management of pharyngitis, tonsillitis, gingivitis, and stomatitis
Mechanism of Action
- Local anti-infective agent belonging to the benzoquinone derivatives
- Exerts bacteriostatic activity primarily against streptococci, pneumococci, and staphylococci in the oral cavity
Contraindications
- Hypersensitivity to ambazone or any excipients in the formulation
- Severe erosive or ulcerative lesions of the oral mucosa where systemic absorption risk is elevated
Adverse Reactions
- Allergic skin reactions (rare)
- Local irritation of the oral mucosa (rare)
- Nausea or gastrointestinal discomfort if swallowed whole
Drug Interactions
- No clinically significant systemic drug interactions identified due to predominantly local action
- Avoid concurrent use of other local antiseptic or antibiotic throat preparations to prevent mucosal irritation
Curated Content: Needs Vetting Before Put to Clinical Use