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RESPIRATORY SYSTEM › THROAT PREPARATIONS › THROAT PREPARATIONS › Antiseptics
dichlorobenzyl alcohol
R02AA03
Forms & Strengths
- Lozenges 0.2% (20 mg per lozenge)
- Mouthwash solution 0.5% w/v
- Throat spray 0.5% w/v
- Topical gel/cream 0.5% for skin
Adult Dosing
- Lozenges: 1‑2 lozenges every 2‑3 h, max 8 per 24 h
- Mouthwash: 10 mL swish for 30 s, 3‑4 times daily
- Throat spray: 1‑2 sprays every 2‑3 h, max 8 sprays/day
Pediatric Dosing
- Children ≥6 y: lozenges 1 lozenge every 3‑4 h, max 4‑5 per day
- Children ≥6 y: mouthwash 5 mL swish 30 s, 2‑3 times daily
- Children <6 y: not recommended for lozenges; use only under medical supervision for mouthwash/gel
Indications
- Symptomatic relief of acute sore throat (pharyngitis, tonsillitis)
- Topical antiseptic for minor oral mucosal infections (stomatitis, gingivitis)
- Adjunctive treatment of minor cutaneous abrasions and superficial burns
Mechanism of Action
- Membrane‑active antiseptic that denatures proteins and disrupts bacterial cell membranes
- Broad‑spectrum bacteriostatic and virucidal activity against Gram‑positive, Gram‑negative bacteria and enveloped viruses
Contraindications
- Known hypersensitivity to dichlorobenzyl alcohol or formulation excipients
- Use of lozenges in children <6 y (risk of choking)
- Severe oral mucosal lesions where irritation could worsen condition
Adverse Reactions
- Transient oral/buccal irritation or burning sensation
- Altered taste (metallic or bitter)
- Rare allergic reactions: urticaria, angio‑edema
- Occasional dry mouth or mild nausea if swallowed excess
Drug Interactions
- No clinically significant systemic interactions (minimal absorption)
- Concurrent use of other oral antiseptics may increase local irritation
- Avoid simultaneous use with alcohol‑based mouthwashes to prevent excessive mucosal drying
Curated Content: Needs Vetting Before Put to Clinical Use