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chlorquinaldol

R02AA11

Forms & Strengths

Cream 0.5% w/w
Ointment 0.5% w/w
Solution 0.5% w/v for topical use

Adult Dosing

Apply a thin film to affected area 2‑3 times daily
Continue for up to 14 days or until lesion resolves

Pediatric Dosing

Same regimen as adults for children ≥2 years
For children <2 years, use only under medical supervision and avoid mucous membranes

Indications

Local bacterial skin infections (impetigo, folliculitis)
Minor wounds, abrasions, cuts
Superficial fungal infections (tinea corporis)

Mechanism of Action

Quinoline‑derived antiseptic that disrupts microbial cell membranes and interferes with protein synthesis

Contraindications

Known hypersensitivity to chlorquinaldol or related quinolines
Use on deep puncture wounds, severe burns, or extensive skin loss
Application to eyes, ears, or mucous membranes

Adverse Reactions

Local erythema, itching, or burning sensation
Contact dermatitis or allergic skin reaction
Rare systemic toxicity with excessive application

Drug Interactions

Minimal systemic absorption; no significant pharmacokinetic interactions
Concurrent use with other topical irritants may increase skin irritation
Occlusive dressings may enhance percutaneous absorption

Curated Content: Needs Vetting Before Put to Clinical Use