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RESPIRATORY SYSTEM › COUGH AND COLD PREPARATIONS › EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS › Expectorants
levoverbenone
R05CA11
Forms & Strengths
- Oral syrup: 0.05%
- Oral drops: 1%
Adult Dosing
- Oral syrup: 10 to 20 mL three times daily
- Oral drops: 30 to 50 drops three times daily
Pediatric Dosing
- Children > 2 years: 5 to 10 mL syrup twice daily or weight-adjusted drops as directed by clinical protocol
- Children < 2 years: contraindicated or use strictly under specialist supervision
Indications
- Symptomatic treatment of acute productive cough
- Adjuvant secretolytic therapy in acute respiratory tract infections
Mechanism of Action
- Acts as a secretolytic and mucokinetic agent in the respiratory tract
- Stimulates bronchial gland secretion to reduce mucus viscosity and facilitate expectoration
Contraindications
- Hypersensitivity to levoverbenone or related terpene derivatives
- History of febrile seizures or epilepsy
- Children with a history of acute laryngeal spasm or asthma
- Infants under 2 years of age due to risk of laryngospasm
Adverse Reactions
- Gastrointestinal upset, nausea, or vomiting
- Allergic skin reactions or pruritus
- Rare risk of neurotoxicity or spasms in infants if misused
Drug Interactions
- Concomitant use with other centrally acting antitussives is not recommended
- May lower seizure threshold when combined with epileptogenic drugs due to terpene content
Curated Content: Needs Vetting Before Put to Clinical Use