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RESPIRATORY SYSTEM › COUGH AND COLD PREPARATIONS › COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS › Other cough suppressants
morclofone
R05DB25
Forms & Strengths
- Oral syrup: 2 mg/mL
- Oral drops: 10 mg/mL
- Tablets: 20 mg
Adult Dosing
- Tablets: 20 mg orally 3 times daily
- Syrup: 10-20 mL (20-40 mg) orally 3 times daily
- Maximum daily dose: 120 mg orally
Pediatric Dosing
- Children > 12 years: Same as adult dosing
- Children 6-12 years: 10 mg orally 3 times daily
- Children 2-6 years: 5 mg orally 3 times daily
Indications
- Symptomatic treatment of non-productive (dry) cough
- Suppression of acute and chronic cough of various etiologies
Mechanism of Action
- Central non-narcotic antitussive agent
- Acts directly on the cough center in the medulla oblongata to elevate the cough threshold without causing respiratory depression or dependence
Contraindications
- Hypersensitivity to morclofone or any excipients in the formulation
- Productive cough with excessive mucus secretions where suppression could cause obstruction
- Severe respiratory insufficiency
- Children under 2 years of age
Adverse Reactions
- Mild drowsiness or sedation
- Dizziness
- Gastrointestinal disturbances (nausea, dyspepsia, dry mouth)
- Hypersensitivity reactions (skin rash, pruritus)
Drug Interactions
- Central nervous system (CNS) depressants (alcohol, sedatives, hypnotics): May potentiate sedative effects
- Expectorants and mucolytics: Concurrent use with antitussives is pharmacologically counterproductive and generally avoided
Curated Content: Needs Vetting Before Put to Clinical Use