← Search & browse all drugs

nitrofural

S01AX04

Forms & Strengths

Ophthalmic solution 0.02%
Topical solution 0.2%
Topical ointment 0.2%

Adult Dosing

Ophthalmic: Instill 1-2 drops into the affected eye(s) 3-4 times daily.
Topical: Apply a small amount to the affected area 2-3 times daily or as needed.

Pediatric Dosing

Safety and efficacy in pediatric patients have not been firmly established.
Use with caution and consult a pediatric specialist for age-appropriate dosing if necessary.

Indications

Treatment of superficial bacterial infections of the eye and surrounding structures
Topical adjunct in the management of second- and third-degree burns
Prevention and treatment of surface bacterial infections in skin grafts and wounds

Mechanism of Action

Broad-spectrum antimicrobial agent that inhibits bacterial enzymes involved in carbohydrate metabolism
Bacteriostatic or bactericidal depending on drug concentration and susceptibility of the organism

Contraindications

Hypersensitivity to nitrofural (nitrofurazone) or any component of the formulation
Known glucose-6-phosphate dehydrogenase (G6PD) deficiency

Adverse Reactions

Local irritation, burning, or stinging upon application
Contact dermatitis and allergic skin reactions
Photosensitivity reactions

Drug Interactions

May be inactivated in the presence of blood, serum, or purulent exudates
Avoid concurrent use of other topical antimicrobial agents on the same site to prevent antagonistic effects or increased irritation

Curated Content: Needs Vetting Before Put to Clinical Use