← Search & browse all drugs

hexamidine

S01AX08

Forms & Strengths

Ophthalmic solution 0.1%

Adult Dosing

1 to 2 drops in the affected eye up to 4 to 6 times daily
Duration of treatment should generally not exceed 7 to 10 days without re-evaluation

Pediatric Dosing

Safety and efficacy in pediatric patients are established based on clinical practice, using adult concentrations
1 drop in the affected eye up to 4 times daily under medical supervision

Indications

Treatment of superficial ocular infections caused by susceptible organisms
Bacterial conjunctivitis and blepharitis

Mechanism of Action

Cationic antiseptic and disinfectant belonging to the diamidine group
Binds to the phospholipid layer of bacterial cell membranes, altering permeability and causing leakage of intracellular constituents
Exhibits bacteriostatic and fungistatic properties against a range of gram-positive and gram-negative pathogens

Contraindications

Hypersensitivity to hexamidine or any components of the formulation
Not for injection or intraocular administration

Adverse Reactions

Transient stinging or burning upon instillation
Allergic contact dermatitis
Ocular irritation or hyperemia in sensitive individuals

Drug Interactions

No significant systemic drug interactions anticipated due to minimal systemic absorption
Avoid simultaneous administration of other topical ophthalmic medications without a 5 to 10-minute interval

Curated Content: Needs Vetting Before Put to Clinical Use