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SENSORY ORGANS › OPHTHALMOLOGICALS › ANTIINFECTIVES › Other antiinfectives
picloxydine
S01AX16
Forms & Strengths
- Ophthalmic solution 0.05%
Adult Dosing
- Instill 1 to 2 drops into the affected eye(s) 2 to 4 times daily
Pediatric Dosing
- Safety and efficacy in pediatric patients are not well established; use with caution per physician direction
Indications
- Treatment of superficial ocular infections caused by susceptible microorganisms, including bacterial conjunctivitis
Mechanism of Action
- Bisbiguanide antiseptic agent that disrupts the cell membrane and wall of susceptible bacteria, leading to leakage of cellular contents and cell death
Contraindications
- Hypersensitivity to picloxydine or any component of the formulation
- Deep-seated ocular infections
Adverse Reactions
- Transient stinging or burning upon instillation
- Mild local irritation
- Allergic conjunctivitis or contact dermatitis in rare cases
Drug Interactions
- No significant systemic drug interactions documented due to minimal systemic absorption
- Avoid concurrent use of other topical ophthalmic medications without at least a 5-minute interval
Curated Content: Needs Vetting Before Put to Clinical Use