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cethexonium

S01AX26

Forms & Strengths

Ophthalmic solution 0.05%

Adult Dosing

Instill 1 to 2 drops into the affected eye(s) up to 4 times daily as needed for antisepsis or minor irritation.

Pediatric Dosing

Safety and efficacy in pediatric patients under 12 years have not been established; use with caution and only as directed by an ophthalmologist.

Indications

Antiseptic for superficial ocular infections
Pre-procedural ocular antisepsis
Relief of minor ocular irritation

Mechanism of Action

Quaternary ammonium antiseptic compound that acts as a cationic surfactant, disrupting cell membranes and causing leakage of intracellular constituents in susceptible microorganisms.

Contraindications

Hypersensitivity to cethexonium or any component of the formulation
Deep-seated ocular infections where topical antisepsis alone is insufficient

Adverse Reactions

Transient stinging or burning upon instillation
Mild ocular hyperemia
Allergic contact dermatitis with prolonged use

Drug Interactions

Incompatible with anionic compounds such as soap and certain ophthalmic preservatives
No major systemic drug interactions expected due to minimal systemic absorption

Curated Content: Needs Vetting Before Put to Clinical Use