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SENSORY ORGANS › OPHTHALMOLOGICALS › MYDRIATICS AND CYCLOPLEGICS › Anticholinergics
scopolamine
S01FA02
Forms & Strengths
- Ophthalmic solution 0.25%
Adult Dosing
- Uveitis: Instill 1 to 2 drops in the eye(s) up to TID as needed.
Pediatric Dosing
- Uveitis (Children > 1 year): Instill 1 drop of 0.25% solution in the eye(s) up to TID.
Indications
- Production of cycloplegia and mydriasis in diagnostic procedures
- Treatment of inflammatory conditions of the uveal tract (uveitis)
Mechanism of Action
- Anticholinergic agent that blocks the responses of the sphincter muscle of the iris and the accommodative muscle of the ciliary body to cholinergic stimulation, producing mydriasis and cycloplegia.
Contraindications
- Hypersensitivity to scopolamine or any component of the formulation
- Primary angle-closure glaucoma or risk of narrow-angle glaucoma
- Children with a previous history of psychotic reaction to scopolamine
Adverse Reactions
- Transient stinging or burning upon instillation
- Blurred vision
- Photophobia
- Increased intraocular pressure
- Systemic anticholinergic effects (dry mouth, tachycardia, flushed skin) with excessive systemic absorption
Drug Interactions
- Concomitant use with other anticholinergic medications may enhance systemic anticholinergic adverse effects
- May antagonize the antiglaucoma effects of cholinergic agonists (e.g., pilocarpine)
Curated Content: Needs Vetting Before Put to Clinical Use