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SENSORY ORGANS › OPHTHALMOLOGICALS › MYDRIATICS AND CYCLOPLEGICS › Sympathomimetics excl. antiglaucoma preparations
ibopamine
S01FB03
Adult Dosing
- 1-2 drops instilled into the conjunctival sac up to 3 times daily for diagnostic mydriasis
Pediatric Dosing
- Safety and efficacy in pediatric patients not established; use with caution if prescribed off-label
Indications
- Induction of mydriasis for diagnostic and therapeutic ophthalmic procedures
Mechanism of Action
- Dopaminergic agonist that stimulates alpha-adrenergic and dopaminergic receptors in the iris sphincter and dilator muscles, producing mydriasis with minimal cycloplegia
Contraindications
- Hypersensitivity to ibopamine or any component of the formulation
- Patients with narrow-angle glaucoma or risk of acute angle closure
Adverse Reactions
- Transient ocular stinging or burning upon instillation
- Increased intraocular pressure
- Conjunctival hyperemia
- Systemic effects rarely include tachycardia and elevated blood pressure
Drug Interactions
- May enhance the pressor effects of systemic sympathomimetic agents
- Additive mydriatic effects when used concomitantly with anticholinergic or other sympathomimetic ophthalmic drops
Curated Content: Needs Vetting Before Put to Clinical Use