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SENSORY ORGANS › OPHTHALMOLOGICALS › DECONGESTANTS AND ANTIALLERGICS › Other antiallergics
epinastine
S01GX10
Forms & Strengths
- ophthalmic solution 0.05% (0.5 mg/mL) single‑dose vials
Adult Dosing
- 1 drop in each affected eye twice daily (morning and evening)
Pediatric Dosing
- 1 drop in each affected eye twice daily for children ≥3 years; safety not established <3 years
Indications
- seasonal and perennial allergic conjunctivitis
Mechanism of Action
- selective H1‑receptor antagonist with mast‑cell stabilising activity; blocks histamine‑induced vasodilation and reduces release of inflammatory mediators
Contraindications
- hypersensitivity to epinastine or any excipient
Adverse Reactions
- transient ocular burning or stinging
- itching or foreign‑body sensation
- blurred vision
- conjunctival hyperemia
- headache
Drug Interactions
- minimal systemic absorption; no significant pharmacokinetic interactions
- caution when used with other topical antihistamines or vasoconstrictors due to additive ocular effects
Curated Content: Needs Vetting Before Put to Clinical Use