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SENSORY ORGANS › OPHTHALMOLOGICALS › DECONGESTANTS AND ANTIALLERGICS › Other antiallergics
alcaftadine
S01GX11
Forms & Strengths
- Alcaftadine ophthalmic solution 0.25% (1 mg/mL)
- Packaged in single‑dose vials or multidose bottles
Adult Dosing
- One drop in each eye once daily
Pediatric Dosing
- One drop in each eye once daily for children ≥3 years; safety not established <3 years
Indications
- Seasonal and perennial allergic conjunctivitis
- Relief of ocular itching, redness, and tearing due to allergy
Mechanism of Action
- Selective H1‑histamine receptor antagonist
- Mast‑cell stabilizer with additional H2, M1, and M3 antagonism
- Inhibits release of inflammatory mediators from conjunctival mast cells
Contraindications
- Known hypersensitivity to alcaftadine or any formulation excipient
Adverse Reactions
- Transient burning or stinging on instillation
- Mild ocular irritation or foreign‑body sensation
- Blurred vision lasting <5 minutes
- Headache
Drug Interactions
- No clinically significant systemic interactions reported
- Caution with concurrent ocular medications (e.g., other antihistamine or steroid drops) that may alter corneal absorption
- Avoid use with contact lenses during dosing to prevent drug dilution
Curated Content: Needs Vetting Before Put to Clinical Use