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ethylmorphine

S01XA06

Forms & Strengths

Ophthalmic drops: 1% to 2% solution

Adult Dosing

Instill 1 to 2 drops into the affected eye(s) 1 to 3 times daily as directed for localized chemosis and analgesia.

Pediatric Dosing

Safety and efficacy in pediatric patients have not been firmly established; use with caution and only under specialist supervision.

Indications

Indicated for use as an ocular decongestant
Used to induce deliberate chemosis in specific corneal conditions to promote absorption
Relief of ocular pain in certain inflammatory conditions

Mechanism of Action

Acts as an opioid derivative acting on local ocular tissues
Induces localized vasodilation and chemosis (edema of the conjunctiva), which historically was believed to increase local circulation and clearance of inflammatory exudates

Contraindications

Hypersensitivity to ethylmorphine or other opioids
Acute infectious conjunctivitis where vasodilation may worsen the infection
Angle-closure glaucoma

Adverse Reactions

Transient ocular stinging or burning upon instillation
Marked conjunctival hyperemia and chemosis (often intentional for the drug's effect)
Blurred vision
Allergic contact dermatitis

Drug Interactions

Concurrent use of other topical ophthalmic vasoconstrictors may lead to additive vascular effects
Local anesthetics may alter absorption when applied simultaneously

Curated Content: Needs Vetting Before Put to Clinical Use