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SENSORY ORGANS › OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS › ANTIINFECTIVES › Antiinfectives
hexamidine
S03AA05
Adult Dosing
- Instill 1 to 2 drops into the affected eye(s) 4 to 6 times daily.
Pediatric Dosing
- Safety and efficacy in pediatric patients are not extensively established; use with caution and under medical supervision based on clinical necessity.
Indications
- Treatment of superficial ocular infections caused by susceptible organisms, including bacterial conjunctivitis and blepharitis.
Mechanism of Action
- Diamidine antiseptic derivative that acts as a cationic surfactant, disrupting cell membrane permeability and precipitating cytoplasmic proteins in susceptible bacteria.
Contraindications
- Hypersensitivity to hexamidine or any components of the formulation
- Use with soft contact lenses during acute infection periods
Adverse Reactions
- Transient stinging or burning upon instillation
- Allergic contact dermatitis
- Ocular irritation and hyperemia
Drug Interactions
- No significant systemic drug interactions identified due to minimal systemic absorption
- Avoid concurrent use of other topical ophthalmic medications without a 5 to 15 minute interval to prevent washout effects
Curated Content: Needs Vetting Before Put to Clinical Use