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iodamide

V08AA03

Forms & Strengths

Injectable solution containing iodamide sodium
Various concentrations for radiographic procedures

Adult Dosing

Dosing varies widely based on specific radiological procedure, route of administration, and equipment used
Typically administered intravascularly or into body cavities under physician supervision

Pediatric Dosing

Dosing is reduced based on age, weight, and clinical condition
Administered under specialized pediatric radiological protocols

Indications

Diagnostic radiocontrast agent used for intravascular and body cavity visualization
Excretory urography and angiography

Mechanism of Action

Contains organically bound iodine that absorbs X-rays, opacifying blood vessels, organs, and tracts through which it passes

Contraindications

Known hypersensitivity to iodinated contrast media
Manifest hyperthyroidism
Severe dehydration

Adverse Reactions

Hypersensitivity reactions ranging from mild rash to anaphylactic shock
Injection site reactions and pain
Nausea and vomiting
Transient renal impairment or contrast-induced nephropathy

Drug Interactions

Increased risk of renal toxicity when co-administered with nephrotoxic drugs
Biguanides (metformin) may need to be withheld to avoid lactic acidosis in renal impairment
Beta-blockers may exacerbate hypersensitivity reactions and reduce responsiveness to treatment

Curated Content: Needs Vetting Before Put to Clinical Use