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VARIOUS › CONTRAST MEDIA › X-RAY CONTRAST MEDIA, IODINATED › Watersoluble, hepatotropic X-ray contrast media
ioglycamic acid
V08AC03
Forms & Strengths
- Intravenous injection/infusion solution (meglumine ioglycamate)
Adult Dosing
- Intravenous cholangiography: 10 to 20 mL of a 30% to 50% solution administered slowly over 5 to 10 minutes
Pediatric Dosing
- Safety and efficacy in pediatric patients not established; use generally avoided
Indications
- Diagnostic visualization of the biliary tract
- Intravenous cholangiography and cholecystography
Mechanism of Action
- Triiodinated benzoic acid derivative containing organically bound iodine that absorbs X-rays
- Selectively excreted by the liver into the bile ducts, allowing radiographic visualization of the gallbladder and biliary tree
Contraindications
- Known hypersensitivity to ioglycamic acid or other iodinated contrast media
- Severe hepatic or renal impairment
- Hyperthyroidism
- Manifest hyperthyroidism
- Plummer's disease
Adverse Reactions
- Nausea and vomiting
- Flushing and sensation of warmth
- Urticaria and pruritus
- Hypotension and dizziness
- Anaphylactoid reactions and severe bronchospasm
Drug Interactions
- Beta-blockers may increase risk of severe hypersensitivity reactions and reduce response to treatment of bronchospasm
- Interleukin-2 may increase risk of delayed hypersensitivity reactions
- Metformin-associated lactic acidosis risk if renal function is impaired post-procedure
Curated Content: Needs Vetting Before Put to Clinical Use