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propyliodone

V08AD03

Forms & Strengths

Aqueous suspension: 50% to 60% w/v
Oily suspension: 50% to 60% w/v in arachis oil

Adult Dosing

Bronchography: 10 mL to 20 mL administered via endotracheal or transtracheal catheter
Dose varies depending on the specific bronchial tree area to be visualized

Pediatric Dosing

Bronchography: 2 mL to 10 mL administered via endotracheal catheter depending on age and size
Use is generally restricted and adjusted based on pediatric body weight and clinical necessity

Indications

Radiographic visualization of the bronchial tree
Diagnostic bronchography for pulmonary lesions, bronchiectasis, and airway obstructions

Mechanism of Action

Contains iodine, which is radiopaque and strongly absorbs X-rays
Provides contrast outlining the mucosal surface of the bronchi during fluoroscopy and radiography

Contraindications

Known hypersensitivity to iodine or iodine-containing contrast media
Severe pulmonary insufficiency or respiratory distress
Active pulmonary hemorrhage or severe asthma

Adverse Reactions

Allergic reactions ranging from rash and urticaria to anaphylaxis
Pulmonary inflammation, lipoid pneumonia (with oily formulations), or granuloma formation
Transient bronchospasm and dyspnea
Iodism (chronic iodine toxicity with prolonged retention)

Drug Interactions

Beta-blockers may increase the risk of severe hypersensitivity reactions and complicate the treatment of bronchospasm
Interferes with thyroid function tests (radioactive iodine uptake) for several weeks following administration

Curated Content: Needs Vetting Before Put to Clinical Use